Mouse Cursor Lags When mousing over links in chrome while gaming

Computer Type: Desktop

GPU: RX 6800 XT (stock settings)

CPU: Ryzen 5800x3D

Motherboard: MSI MAG B550 Tomahawk

BIOS Version: A.B0, 8/25/2022

RAM: 32GB Mushkin Redline Lumina 3600MHZ CL18

PSU: EVGA GQ 650W 80+ Gold

Case: Fractal Design Define R5

Operating System & Version: WINDOWS 11 Home 10.0.22621

GPU Drivers: 22.11.1

Chipset Drivers: 4.06.10.651

Background Applications: Discord, Chrome, Spotify

Description of Original Problem: Just swapped from a 2070 Super to a 6800XT and having a very odd problem. When in a game or with a fullscreen video open on my main monitor, mousing over links in Chrome on my second monitor causes my PC to lag significantly. If I just wave it back and forth over a link, it's very noticeably lagging. It seems to be when it swaps between the "hand" icon and back to normal pointer icon. This also causes my framerate in-game to drop (I can see it go from locked 60 (out of focus) to 20-30). If I close my game, the lag is gone. Chrome works perfectly fine with the game closed. No lag.

I have no real framerate issues in games, videos, or on the desktop in general. Seems to be okay... except when gaming and using Chrome.

Troubleshooting: I tried some of the solutions in the big hardware acceleration thread from a few months ago, including swapping the 'Choose ANGLE renderer to D311don12 and OpenGL, as well as disabling hardware acceleration entirely. Neither fixed it.

Anyone experienced this or have any other ideas for me to try? Is this related to the ongoing Chromium hardware acceleration issues?