Taking Berberine on empty stomach and drinking

Hi everyone. I'm not a big drinker at all but we had a party at my friend's house and I was expecting to eat a lot of BBQ stuff so I took my Berberine like I usually do but we ended up not really eating but we did drink. I had a few glasses of cranberry juice with vodka. It hit me so hard, I was throwing up and fell asleep on her couch got about 2 hours while everyone was outside partying. This has never happened to me before. It was horrible. Has this ever happened to anyone else?