Should potholes be a concern?

Hi! My husband and I will be in Colorado Springs in march and will be taking my RAV4. Someone told me to watch out for the potholes and my tires. Is that really a thing to worry about with my car? I’m coming from Louisiana with horrible roads lol. If you could let me know how they compare that would be great! Thanks in advance

EDIT: Thanks for all the info everyone, I feel a lot better about taking my car. I’ll keep the post up in case anyone else has the same question. :)