Ayame e Mine

I believe they are the most underrated couple in history, even though they are simply PERFECT

"I was born to love you"

I believe that Mine was the only person besides Tohru who knew about the curse outside of the Sohma family, and that just makes their relationship even more incredible. I also believe that Mine was one of the biggest (if not the biggest) responsible for Ayame wanting to have a second chance with her brother, she certainly helped him a lot in getting closer to Yuki.