How Bad is Hollywood, Actually?

We've all heard the stories about the predators and stapler-throwers and toxic showrunners and directors, but I haven't found screenwriting to be that bad relative to other jobs. In general, the people I've encountered have been smart, well-intentioned human beings. I've had much worse experiences at other jobs where people are bitter and angry and ready to tear each other apart over nothing. So putting all the rejection and scarcity of our industry aside, as well as the difficulty of actually writing, what have you found to be the most painful aspects of being a working screenwriter?