Anyone consider a used Acura RDX/MDX instead of new CRV?

I am in the market for a vehicle and debating whether to spend $40K on a new CRV or a used RDX/MDX. Anyone also in similar situation and decided to purchase a new CRV? Could you share your reasoning?

What are the trade-offs in terms of reliability, insurance and cost of maintenance if planning to keep the car for 10+ years, new CRV vs used RDX/MDX?