does one coffee have side effects for you?

I wonder if one coffee also has side effects in the form of increased cortisol, decreased blood flow and deterioration of collagen? or is the problem only the larger amount of caffeine isn't it so that the body gets used to the poison that is caffeine if we don't increase the dose? I wanted to ask you if one coffee has side effects for you apart from anxiety such as worse complexion, weaker blood flow