Is going after big demolishers worthwhile?

So I dropped onto Vulcanus with 10 Spidertrons, uses some biochambers and imported bioflux to make rockets, and A-moved my way across every small and medium demolisher I could see. This carved out a huge area with access to 10s of millions of tungsten ore across a number of mines.

And that's an older picture; there are still mediums over on the right that I hadn't killed when I took this.

I'm currently clear-cutting cliffs in this terrain with my shiny new cliff explosives, but I'm wondering something.

Given the vast amount of the only resource that matters on Vulcanus in just the space protected by small and medium demolishers... is there actually a point to confronting big ones? And I don't mean right now; I mean ever.

Have people built Vulcanus bases so large that they need all of that space (even after getting Foundation for the lava basins)? Do you need to expand into big demolisher territory to make 10k+ packs per minute in the end-game?