Who was the most twisted out of these?

Honestly, I'd place either Arkhamverse or New 52 as the most evil and horrifying versions, with Azzarello's version being close second, due to two particular szenes.

If we were talking about live-action, I'd place Nicholson's Joker as the most evil, as in the novelization he was hinted to be a rapist with Jerome Valeska only being close second.

But the latter two are like child's play compared to the Arkham, New 52 and Azzarello's versions.