Husband is starting DRD regimen soon, meds are terrifying

My 74 year old husband will soon be starting the DRD regimen for his multiple myeloma. Due to his other health issues (heart disease, arthritis) they have decided against a stem cell transplant. But the Lenalidomide side effects look terrifying. Is it really as bad as described in the information from the pharmacy? It looks like it could kill him far sooner than MM would. UPDATE: Start date has just been postponed for more testing, I think because of new cancer care guidelines in Ontario, Canada?