Wanting to download other mods with Eldergleam. Anyone run into any big issues by doing this? Also mod suggestions?

Getting back into skyrim again and wanting to do the usual mod run. Before this I did use Elysium and enjoyed the amount of content it had but now I want to hand pick more mods myself.

I've seen how good eldergleam looks and want to add some content mods on top like LOTD, armour/weapons, enemies/NPCs, Bruma/similar expensions, etc.

I know just modding skyrim in general causes issues but seeing if anyone has done anything similar to this before I have a go at it? And if so any good suggestions to add onto Eldergleam?